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doi: 10.1016/j.esxm.2021.100343. Epub 2021 May 14.

Restorative Therapies for Erectile Dysfunction: Position Statement From the Sexual Medicine Guild of Due north America (SMSNA)

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• PMID: 34000480
• PMCID: PMC8240368
• DOI: 10.1016/j.esxm.2021.100343

Free PMC article

Review

Restorative Therapies for Erectile Dysfunction: Position Statement From the Sexual Medicine Society of North America (SMSNA)

James Fifty Liu  et al. Sex Med. 2021 Jun .

Free PMC article

Abstract

Introduction: Current non-invasive treatments for erectile dysfunction (ED) include oral medications, intracavernosal injections, and vacuum-assisted devices. Though these therapies work well for many, a subset of patients have contraindications or are unsatisfied with these options. Restorative therapies for ED are a new frontier of treatments focused on regenerating diseased tissue and providing a potential "cure" for ED.

Aim: The aim of this position statement is to examine existing clinical trial data for restorative therapies and identify elements that require further enquiry before widespread adoption.

Methods: A literature review was performed to place all clinical trials performed with regenerative therapy for ED. This includes treatments such as stem prison cell therapy (SCT), platelet rich plasma (PRP), and restorative related technologies similar low-intensity shockwave therapy (LiSWT).

Master outcome measures: Near clinical trials in restorative therapies were assessed for safety, feasibility, or efficacy. This included recording adverse events, changes in sexual function and erectile function questionnaires, and diagnostics measures.

Results: To appointment there is an absenteeism of robust clinical data supporting the efficacy of restorative therapies regarding ED, though technologies such as LiSWT have established relative prophylactic.

Conclusions: Restorative therapies are a promising technology that represents a new frontier of handling geared towards reversing disease pathology rather than just treating symptoms. Even so, current published clinical studies are express. Hereafter work needs to exist adequately powered, multi-eye, randomized, sham/placebo-controlled trials in well-characterized patient populations to ensure safety and demonstrate efficacy. Until these studies are done, restorative therapies should be reserved for clinical trials and not offered in routine clinical practise. Liu JL, Chu KY, Gabrielson AT, et al. Restorative Therapies for Erectile Dysfunction: Position Statement From the Sexual Medicine Society of Due north America (SMSNA). J Sexual activity Med 2021;9:100343.

Keywords: Erectile dysfunction; Low intensity daze wave therapy; Platelet rich plasma; Restorative therapies; Stem cell therapy; Stromal vascular fraction.

Copyright © 2021 The Authors. Published past Elsevier Inc. All rights reserved.

Figures

Figure 1

LiSWT mechanism of activeness compared to radial wave therapy.

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Source: https://pubmed.ncbi.nlm.nih.gov/34000480/

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